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BRCA1 and Its Network of Interacting Partners
BRCA1 is a large multi-domain protein with a pivotal role in maintaining genome stability and cell cycle progression. Germline mutations in the BRCA1 gene confer an estimated lifetime risk of 60%–80% for breast cancer and 15%–60% for ovarian cancer. Many of the germline mutations associated with can...
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| Main Authors: | , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
MDPI
2012
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4009870/ https://ncbi.nlm.nih.gov/pubmed/24832651 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/biology2010040 |
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