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BRCA1 tumor suppressor network: focusing on its tail
Germline mutations of the BRCA1 tumor suppressor gene are a major cause of familial breast and ovarian cancer. BRCA1 plays critical roles in the DNA damage response that regulates activities of multiple repair and checkpoint pathways for maintaining genome stability. The BRCT domains of BRCA1 consti...
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| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
BioMed Central
2012
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| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3315748/ https://ncbi.nlm.nih.gov/pubmed/22369660 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/2045-3701-2-6 |
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