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The RON Receptor Tyrosine Kinase in Pancreatic Cancer Pathogenesis and Its Potential Implications for Future Targeted Therapies

Pancreatic cancer remains a devastating disease with a mortality rate that has not changed substantially in decades. Novel therapies are therefore desperately needed. The RON receptor tyrosine kinase has been identified as an important mediator of KRAS oncogene addiction and is over-expressed in the...

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Detalhes bibliográficos
Main Authors: Kang, Chang Moo, Babicky, Michele L., Lowy, Andrew M.
Formato: Artigo
Idioma:Inglês
Publicado em: 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4009395/
https://ncbi.nlm.nih.gov/pubmed/24518495
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1097/MPA.0000000000000088
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