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Identification of residues essential for catalysis and binding of calmodulin in Bordetella pertussis adenylate cyclase by site-directed mutagenesis.

In order to identify molecular features of the calmodulin (CaM) activated adenylate cyclase of Bordetella pertussis, a truncated cya gene was fused after the 459th codon in frame with the alpha-lacZ' gene fragment and expressed in Escherichia coli. The recombinant, 604 residue long protein was...

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Detalhes bibliográficos
Main Authors: Glaser, P, Elmaoglou-Lazaridou, A, Krin, E, Ladant, D, Bârzu, O, Danchin, A
Formato: Artigo
Idioma:Inglês
Publicado em: 1989
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC400898/
https://ncbi.nlm.nih.gov/pubmed/2542030
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