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Involvement of miR-605 and miR-34a in the DNA Damage Response Promotes Apoptosis Induction

MicroRNAs are key regulators of gene expression at the posttranscriptional level. In this study, we focus on miR-605 and miR-34a, which are direct transcriptional targets of p53 and in turn enhance its tumor suppressor function by acting upstream and downstream of it, respectively. miR-605 promotes...

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Detalles Bibliográficos
Autores principales: Zhou, Chun-Hong, Zhang, Xiao-Peng, Liu, Feng, Wang, Wei
Formato: Artigo
Lenguaje:Inglês
Publicado: The Biophysical Society 2014
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC4008794/
https://ncbi.nlm.nih.gov/pubmed/24739178
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bpj.2014.02.032
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