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Expanding P450 catalytic reaction space through evolution and engineering

Advances in protein and metabolic engineering have led to wider use of enzymes to synthesize important molecules. However, many desirable transformations are not catalyzed by any known enzyme, driving interest in understanding how new enzymes can be created. The cytochrome P450 enzyme family, whose...

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Hlavní autoři: McIntosh, John A., Farwell, Christopher C., Arnold, Frances H.
Médium: Artigo
Jazyk:Inglês
Vydáno: 2014
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4008644/
https://ncbi.nlm.nih.gov/pubmed/24658056
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cbpa.2014.02.001
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