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Expanding P450 catalytic reaction space through evolution and engineering

Advances in protein and metabolic engineering have led to wider use of enzymes to synthesize important molecules. However, many desirable transformations are not catalyzed by any known enzyme, driving interest in understanding how new enzymes can be created. The cytochrome P450 enzyme family, whose...

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Autors principals: McIntosh, John A., Farwell, Christopher C., Arnold, Frances H.
Format: Artigo
Idioma:Inglês
Publicat: 2014
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4008644/
https://ncbi.nlm.nih.gov/pubmed/24658056
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cbpa.2014.02.001
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