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Expanding P450 catalytic reaction space through evolution and engineering

Advances in protein and metabolic engineering have led to wider use of enzymes to synthesize important molecules. However, many desirable transformations are not catalyzed by any known enzyme, driving interest in understanding how new enzymes can be created. The cytochrome P450 enzyme family, whose...

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Bibliografiske detaljer
Main Authors: McIntosh, John A., Farwell, Christopher C., Arnold, Frances H.
Format: Artigo
Sprog:Inglês
Udgivet: 2014
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4008644/
https://ncbi.nlm.nih.gov/pubmed/24658056
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cbpa.2014.02.001
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