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Polycystin-1: a master regulator of intersecting cystic pathways

Autosomal dominant polycystic kidney disease (ADPKD) is the most common potentially lethal monogenic disorder, with more than 12 million cases worldwide. The two causative genes for ADPKD, PKD1 and PKD2, encode protein products polycystin-1 (PC1) and polycystin-2 (PC2 or TRPP2), respectively. Recent...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Egile Nagusiak: Fedeles, Sorin V., Gallagher, Anna-Rachel, Somlo, Stefan
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: 2014
Gaiak:
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC4008641/
https://ncbi.nlm.nih.gov/pubmed/24491980
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.molmed.2014.01.004
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