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Polycystin-1: a master regulator of intersecting cystic pathways

Autosomal dominant polycystic kidney disease (ADPKD) is the most common potentially lethal monogenic disorder, with more than 12 million cases worldwide. The two causative genes for ADPKD, PKD1 and PKD2, encode protein products polycystin-1 (PC1) and polycystin-2 (PC2 or TRPP2), respectively. Recent...

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Bibliografski detalji
Glavni autori: Fedeles, Sorin V., Gallagher, Anna-Rachel, Somlo, Stefan
Format: Artigo
Jezik:Inglês
Izdano: 2014
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4008641/
https://ncbi.nlm.nih.gov/pubmed/24491980
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.molmed.2014.01.004
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