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Functional analysis of the ligand binding site of EGF-receptor utilizing chimeric chicken/human receptor molecules.

The epidermal growth factor (EGF)-receptor is composed of an extracellular ligand-binding region connected by a single transmembrane region to the cytoplasmic kinase domain. In spite of its importance for understanding signal transduction, the ligand-binding domain of the EGF-receptor is not yet def...

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Autors principals: Lax, I, Bellot, F, Howk, R, Ullrich, A, Givol, D, Schlessinger, J
Format: Artigo
Idioma:Inglês
Publicat: 1989
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC400822/
https://ncbi.nlm.nih.gov/pubmed/2785915
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