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Functional analysis of the ligand binding site of EGF-receptor utilizing chimeric chicken/human receptor molecules.

The epidermal growth factor (EGF)-receptor is composed of an extracellular ligand-binding region connected by a single transmembrane region to the cytoplasmic kinase domain. In spite of its importance for understanding signal transduction, the ligand-binding domain of the EGF-receptor is not yet def...

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Udgivet i:EMBO J
Principais autores: Lax, I, Bellot, F, Howk, R, Ullrich, A, Givol, D, Schlessinger, J
Format: Artigo
Sprog:Inglês
Udgivet: Nature Publishing Group 1989
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC400822/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/2785915/
https://ncbi.nlm.nih.govhttps://doi.org/10.1002/j.1460-2075.1989.tb03393.x
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