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Mechanisms of m-cresol induced protein aggregation studied using a model protein cytochrome c()

Multi-dose protein formulations require an effective antimicrobial preservative (AP) to inhibit microbial growth during long-term storage of unused formulations. m-cresol is one such AP, but has been shown to cause protein aggregation. However, the fundamental physical mechanisms underlying such AP-...

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Sonraí Bibleagrafaíochta
Main Authors: Singh, Surinder M., Hutchings, Regina L., Mallela, Krishna M.G.
Formáid: Artigo
Teanga:Inglês
Foilsithe: 2011
Ábhair:
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC4008150/
https://ncbi.nlm.nih.gov/pubmed/21229618
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/jps.22426
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