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Integrated genome-wide genotyping and gene expression profiling reveals BCL11B as a putative oncogene in acute myeloid leukemia with 14q32 aberrations

Acute myeloid leukemia is a neoplasm characterized by recurrent molecular aberrations traditionally demonstrated by cytogenetic analyses. We used high density genome-wide genotyping and gene expression profiling to reveal acquired cryptic abnormalities in acute myeloid leukemia. By genome-wide genot...

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Autores principales: Abbas, Saman, Sanders, Mathijs A., Zeilemaker, Annelieke, Geertsma-Kleinekoort, Wendy M.C., Koenders, Jasper E., Kavelaars, Francois G., Abbas, Zabiollah G., Mahamoud, Souad, Chu, Isabel W.T., Hoogenboezem, Remco, Peeters, Justine K., van Drunen, Ellen, van Galen, Janneke, Beverloo, H. Berna, Löwenberg, Bob, Valk, Peter J.M.
Formato: Artigo
Lenguaje:Inglês
Publicado: Ferrata Storti Foundation 2014
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC4008111/
https://ncbi.nlm.nih.gov/pubmed/24441149
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3324/haematol.2013.095604
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