A carregar...
Aminoindazole PDK1 Inhibitors: A Case Study in Fragment-Based Drug Discovery
[Image: see text] Fragment screening of phosphoinositide-dependent kinase-1 (PDK1) in a biochemical kinase assay afforded hits that were characterized and prioritized based on ligand efficiency and binding interactions with PDK1 as determined by NMR. Subsequent crystallography and follow-up screenin...
Na minha lista:
| Main Authors: | , , , , , , , |
|---|---|
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
American Chemical Society
2010
|
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4007849/ https://ncbi.nlm.nih.gov/pubmed/24900229 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/ml100136n |
| Tags: |
Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!
|