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Fragment-based inhibitor discovery against β-lactamase
The production of β-lactamase is one of the primary resistance mechanisms used by Gram-negative bacterial pathogens to counter β-lactam antibiotics, such as penicillins, cephalosporins and carbapenems. There is an urgent need to develop novel β-lactamase inhibitors in response to ever evolving β-lac...
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| Main Authors: | , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2014
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4111090/ https://ncbi.nlm.nih.gov/pubmed/24635522 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4155/fmc.14.10 |
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