Two different virus-inducible elements are required for human beta-interferon gene regulation.

We show that the human beta-interferon gene promoter contains two different virus-inducible regulatory elements, PRDI and PRDII (positive regulatory domains I and II). A single copy of either element alone has no discernible transcriptional activity in mouse fibroblasts. However, multiple copies of...

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Pubblicato in:	EMBO J
Autori principali:	Fan, C M, Maniatis, T
Natura:	Artigo
Lingua:	Inglês
Pubblicazione:	Nature Publishing Group 1989
Soggetti:	Research Article
Accesso online:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC400777/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/2540952/ https://ncbi.nlm.nih.govhttps://doi.org/10.1002/j.1460-2075.1989.tb03353.x
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