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Two different virus-inducible elements are required for human beta-interferon gene regulation.

We show that the human beta-interferon gene promoter contains two different virus-inducible regulatory elements, PRDI and PRDII (positive regulatory domains I and II). A single copy of either element alone has no discernible transcriptional activity in mouse fibroblasts. However, multiple copies of...

Ausführliche Beschreibung

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Bibliografische Detailangaben
Veröffentlicht in:EMBO J
Hauptverfasser: Fan, C M, Maniatis, T
Format: Artigo
Sprache:Inglês
Veröffentlicht: Nature Publishing Group 1989
Schlagworte:
Online-Zugang:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC400777/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/2540952/
https://ncbi.nlm.nih.govhttps://doi.org/10.1002/j.1460-2075.1989.tb03353.x
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