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Regulated expression of an extrachromosomal human beta-interferon gene in mouse cells.

Beta(fibroblast)-interferon mRNA and protein are induced by the synthetic double-stranded RNA poly(I) X poly(C) in cultured human fibroblasts. To study the mechanism of this induction, we have isolated a human beta-interferon gene and inserted it in a vector plasmid containing DNA of the bovine papi...

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Bibliographic Details
Main Authors: Zinn, K, Mellon, P, Ptashne, M, Maniatis, T
Format: Artigo
Language:Inglês
Published: 1982
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC346792/
https://ncbi.nlm.nih.gov/pubmed/6956899
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