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Novel Benzofurans with (99m)Tc Complexes as Probes for Imaging Cerebral β-Amyloid Plaques

[Image: see text] Two novel benzofuran derivatives coupled with (99m)Tc complexes were tested as probes for imaging cerebral β-amyloid plaques using single photon emission tomography. Although both derivatives bound to Aβ(1−42) aggregates, (99m)Tc-BAT-BF showed higher affinity than (99m)Tc-MAMA-BF....

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Bibliografische gegevens
Hoofdauteurs: Ono, Masahiro, Fuchi, Yasufumi, Fuchigami, Takeshi, Kobashi, Nobuya, Kimura, Hiroyuki, Haratake, Mamoru, Saji, Hideo, Nakayama, Morio
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: American Chemical Society 2010
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4007700/
https://ncbi.nlm.nih.gov/pubmed/24900230
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/ml100140d
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