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Synthesis and Evaluation of Novel Chalcone Derivatives with (99m)Tc/Re Complexes as Potential Probes for Detection of β-Amyloid Plaques
[Image: see text] Four (99m)Tc-labeled chalcone derivatives and their corresponding rhenium analogues were tested as potential probes for imaging β-amyloid plaques. The chalcones showed higher affinity for Aβ(1−42) aggregates than did (99m)Tc complexes. In sections of brain tissue from an animal mod...
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| Main Authors: | , , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
American Chemical Society
2010
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| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3368688/ https://ncbi.nlm.nih.gov/pubmed/22778849 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/cn100042d |
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