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BODIPY-Based Molecular Probe for Imaging of Cerebral β-Amyloid Plaques
[Image: see text] We designed and synthesized a BODIPY-based probe (BAP-1) for the imaging of β-amyloid plaques in the brain. In binding experiments in vitro, BAP-1 showed excellent affinity for synthetic Aβ aggregates. β-Amyloid plaques in Tg2576 mouse brain were clearly visualized with BAP-1. In a...
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| Main Authors: | , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
American Chemical
Society
2012
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| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3369805/ https://ncbi.nlm.nih.gov/pubmed/22860198 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/cn3000058 |
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