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Downstream signaling and genome-wide regulatory effects of PTK7 pseudokinase and its proteolytic fragments in cancer cells
BACKGROUND: The full-length membrane protein tyrosine kinase 7 (PTK7) pseudokinase, an important component of the planar cell polarity and the Wnt canonical and non-canonical pathways, is a subject of step-wise proteolysis in cells and tissues. The proteolysis of PTK7 involves membrane type-matrix m...
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| Autori principali: | , |
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| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
BioMed Central
2014
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| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4007575/ https://ncbi.nlm.nih.gov/pubmed/24618420 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1478-811X-12-15 |
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