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Protein-tyrosine Pseudokinase 7 (PTK7) Directs Cancer Cell Motility and Metastasis

It is well established that widely expressed PTK7 is essential for vertebrate tissue morphogenesis. In cancer, the functionality of PTK7 is selectively regulated by membrane type-1 matrix metalloproteinase (MT1-MMP), ADAMs (a disintegrin domain and metalloproteinases), and γ-secretase proteolysis. H...

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Detalhes bibliográficos
Principais autores: Golubkov, Vladislav S., Prigozhina, Natalie L., Zhang, Yong, Stoletov, Konstantin, Lewis, John D., Schwartz, Phillip E., Hoffman, Robert M., Strongin, Alex Y.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4148854/
https://ncbi.nlm.nih.gov/pubmed/25006253
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M114.574459
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