Glycosylphosphatidylinositol Anchoring Directs the Assembly of Sup35NM Protein into Non-fibrillar, Membrane-bound Aggregates

In prion-infected hosts, PrPSc usually accumulates as non-fibrillar, membrane-bound aggregates. Glycosylphosphatidylinositol (GPI) anchor-directed membrane association appears to be an important factor controlling the biophysical properties of PrPSc aggregates. To determine whether GPI anchoring can...

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Gorde:
Xehetasun bibliografikoak
Egile Nagusiak: Marshall, Karen E., Offerdahl, Danielle K., Speare, Jonathan O., Dorward, David W., Hasenkrug, Aaron, Carmody, Aaron B., Baron, Gerald S.
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: American Society for Biochemistry and Molecular Biology 2014
Gaiak:
Protein Structure and Folding
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC4007424/
https://ncbi.nlm.nih.gov/pubmed/24627481
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M114.556639
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