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In vivo evidence for the fibrillar structures of Sup35 prions in yeast cells

Yeast prion [PSI(+)] is caused by aggregated structures of the Sup35 protein. Although Sup35 forms typical amyloid fibrils in vitro, there is no direct evidence for the fibrillar structures of Sup35 in vivo. We analyzed [PSI(+)] cells in which Sup35 fused with green fluorescent protein (GFP) formed...

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Bibliografiska uppgifter
Huvudupphovsmän: Kawai-Noma, Shigeko, Pack, Chan-Gi, Kojidani, Tomoko, Asakawa, Haruhiko, Hiraoka, Yasushi, Kinjo, Masataka, Haraguchi, Tokuko, Taguchi, Hideki, Hirata, Aiko
Materialtyp: Artigo
Språk:Inglês
Publicerad: The Rockefeller University Press 2010
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Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC2930275/
https://ncbi.nlm.nih.gov/pubmed/20643880
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1083/jcb.201002149
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