In vivo evidence for the fibrillar structures of Sup35 prions in yeast cells

Yeast prion [PSI(+)] is caused by aggregated structures of the Sup35 protein. Although Sup35 forms typical amyloid fibrils in vitro, there is no direct evidence for the fibrillar structures of Sup35 in vivo. We analyzed [PSI(+)] cells in which Sup35 fused with green fluorescent protein (GFP) formed...

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Detalhes bibliográficos
Main Authors: Kawai-Noma, Shigeko, Pack, Chan-Gi, Kojidani, Tomoko, Asakawa, Haruhiko, Hiraoka, Yasushi, Kinjo, Masataka, Haraguchi, Tokuko, Taguchi, Hideki, Hirata, Aiko
Formato: Artigo
Idioma:Inglês
Publicado em: The Rockefeller University Press 2010
Assuntos:
Research Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2930275/
https://ncbi.nlm.nih.gov/pubmed/20643880
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1083/jcb.201002149
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