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Xanthurenic acid translocates proapoptotic Bcl-2 family proteins into mitochondria and impairs mitochondrial function

BACKGROUND: Xanthurenic acid is an endogenous molecule produced by tryptophan degradation, produced in the cytoplasm and mitochondria. Its accumulation can be observed in aging-related diseases, e.g. senile cataract and infectious disease. We previously reported that xanthurenic acid provokes apopto...

詳細記述

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書誌詳細
主要な著者: Malina, Halina Z, Hess, Otto M
フォーマット: Artigo
言語:Inglês
出版事項: BioMed Central 2004
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC400728/
https://ncbi.nlm.nih.gov/pubmed/15068490
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2121-5-14
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