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Xanthurenic acid translocates proapoptotic Bcl-2 family proteins into mitochondria and impairs mitochondrial function
BACKGROUND: Xanthurenic acid is an endogenous molecule produced by tryptophan degradation, produced in the cytoplasm and mitochondria. Its accumulation can be observed in aging-related diseases, e.g. senile cataract and infectious disease. We previously reported that xanthurenic acid provokes apopto...
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| Main Authors: | , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
BioMed Central
2004
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| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC400728/ https://ncbi.nlm.nih.gov/pubmed/15068490 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2121-5-14 |
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