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Lens epithelial cell apoptosis and intracellular Ca(2+) increase in the presence of xanthurenic acid

BACKGROUND: Xanthurenic acid is an endogenous product of tryptophan degradation by indoleamine 2,3-dioxygenase (IDO). We have previously reported that IDO is present in mammalian lenses, and xanthurenic acid is accumulated in the lenses with aging. Here, we studied the involvement of xanthurenic aci...

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Bibliografiske detaljer
Main Authors: Malina, Halina, Richter, Christoph, Frueh, Beatrice, Hess, Otto M
Format: Artigo
Sprog:Inglês
Udgivet: BioMed Central 2002
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC103667/
https://ncbi.nlm.nih.gov/pubmed/11934353
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2415-2-1
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