Llwytho...

Pyruvate minimizes rtPA toxicity from in vitro oxygen-glucose deprivation and reoxygenation

Clinical application of recombinant tissue plasminogen activator (rtPA) for stroke is limited by hemorrhagic transformation, which narrows rtPA’s therapeutic window. In addition, mounting evidence indicates that rtPA is potentially neurotoxic if it traverses a compromised blood brain barrier. Here,...

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Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Prif Awduron: Ryou, Myoung-Gwi, Choudhury, Gourav Roy, Winters, Ali, Xie, Luokun, Mallet, Robert T., Yang, Shao-Hua
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: 2013
Pynciau:
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC4007160/
https://ncbi.nlm.nih.gov/pubmed/23891792
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.brainres.2013.07.029
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