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Activation of a Gq-coupled membrane estrogen receptor rapidly attenuates α(2)-adrenoceptor-induced antinociception via an ERK I/II-dependent, non-genomic mechanism in the female rat
Though sex differences in pain and analgesia are known, underlying mechanisms remain elusive. This study addresses the selective contribution of membrane estrogen receptors (mER) and mER-initiated non-genomic signaling mechanisms in our previously reported estrogen-induced attenuation of α(2)- adren...
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| Main Authors: | , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado: |
2014
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| Assuntos: | |
| Acceso en liña: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4007140/ https://ncbi.nlm.nih.gov/pubmed/24613724 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.neuroscience.2014.02.040 |
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