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The Dual Roles Of Geminin During Trophoblast Proliferation And Differentiation

Geminin is a protein involved in both DNA replication and cell fate acquisition. Although it is essential for mammalian preimplantation development, its role remains unclear. In one study, ablation of the geminin gene (Gmnn) in mouse preimplantation embryos resulted in apoptosis, suggesting that gem...

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Detalles Bibliográficos
Main Authors: de Renty, Christelle, Kaneko, Kotaro J., DePamphilis, Melvin L.
Formato: Artigo
Idioma:Inglês
Publicado: 2014
Assuntos:
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC4007048/
https://ncbi.nlm.nih.gov/pubmed/24412371
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ydbio.2013.12.034
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