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Checkpoint Kinase 1 Prevents Cell Cycle Exit Linked to Terminal Cell Differentiation
Trophoblast stem (TS) cells proliferate in the presence of fibroblast growth factor 4, but in its absence, they differentiate into polyploid trophoblast giant (TG) cells that remain viable but nonproliferative. Differentiation is coincident with expression of the cyclin-dependent kinase (CDK)-specif...
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| Main Authors: | , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
American Society for Microbiology
2011
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3187358/ https://ncbi.nlm.nih.gov/pubmed/21791608 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.05723-11 |
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