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Replication of TPMT and ABCC3 Genetic Variants Highly Associated With Cisplatin-Induced Hearing Loss in Children

Cisplatin is a widely used chemotherapeutic agent for the treatment of solid tumors. A serious complication of cisplatin treatment is permanent hearing loss. The aim of this study was to replicate previous genetic findings in an independent cohort of 155 pediatric patients. Associations were replica...

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Hlavní autoři: Pussegoda, K, Ross, CJ, Visscher, H, Yazdanpanah, M, Brooks, B, Rassekh, SR, Zada, YF, Dubé, M-P, Carleton, BC, Hayden, MR
Médium: Artigo
Jazyk:Inglês
Vydáno: 2013
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4006820/
https://ncbi.nlm.nih.gov/pubmed/23588304
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/clpt.2013.80
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