The Role of Inherited TPMT and COMT Genetic Variation in Cisplatin-induced Ototoxicity in Children with Cancer

Ototoxicity is a debilitating side effect of platinating agents with substantial inter-patient variability. We sought to evaluate the association of TPMT and COMT genetic variations with cisplatin-related hearing damage in the context of frontline pediatric cancer treatment protocols. In 213 childre...

Volledige beschrijving

Bewaard in:
Bibliografische gegevens
Hoofdauteurs: Yang, Jun J., Lim, Joshua Yew-Suang, Huang, Jie, Bass, Johnnie, Wu, Jianrong, Wang, Chong, Fang, Jie, Stewart, Elizabeth, Harstead, Elaine H., Shuyu, E, Robinson, Giles W., Evans, William E., Pappo, Alberto, Zuo, Jian, Relling, Mary V., Onar-Thomas, Arzu, Gajjar, Amar, Stewart, Clinton F.
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: 2013
Onderwerpen:
Article
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3883563/
https://ncbi.nlm.nih.gov/pubmed/23820299
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/clpt.2013.121
Tags: Voeg label toe
Geen labels, Wees de eerste die dit record labelt!

Gelijkaardige items