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The Spatiotemporal Program of DNA Replication Is Associated with Specific Combinations of Chromatin Marks in Human Cells

The duplication of mammalian genomes is under the control of a spatiotemporal program that orchestrates the positioning and the timing of firing of replication origins. The molecular mechanisms coordinating the activation of about [Image: see text] predicted origins remain poorly understood, partly...

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Detalhes bibliográficos
Main Authors: Picard, Franck, Cadoret, Jean-Charles, Audit, Benjamin, Arneodo, Alain, Alberti, Adriana, Battail, Christophe, Duret, Laurent, Prioleau, Marie-Noelle
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4006723/
https://ncbi.nlm.nih.gov/pubmed/24785686
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pgen.1004282
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