A carregar...
Revertant Mutation Releases Confined Lethal Mutation, Opening Pandora's Box: A Novel Genetic Pathogenesis
When two mutations, one dominant pathogenic and the other “confining” nonsense, coexist in the same allele, theoretically, reversion of the latter may elicit a disease, like the opening of Pandora's box. However, cases of this hypothetical pathogenic mechanism have never been reported. We descr...
Na minha lista:
| Main Authors: | , , , , , , |
|---|---|
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Public Library of Science
2014
|
| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4006701/ https://ncbi.nlm.nih.gov/pubmed/24785414 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pgen.1004276 |
| Tags: |
Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!
|