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The Pivotal Role of mTORC2 and Involvement of Ribosomal Protein S6 in Cardioprotective Signaling

RATIONALE: There is tight coupling between Akt activation and suppression of cell death. Full Akt activation requires mTOR complex 2 (mTORC2), but the regulation of mTORC2 is unclear. OBJECTIVE: To gain new insights into mechanisms of mTORC2/Akt signaling. METHODS AND RESULTS: The role of mTORC2 in...

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Detalhes bibliográficos
Main Authors: Yano, Toshiyuki, Ferlito, Marcella, Aponte, Angel, Kuno, Atsushi, Miura, Tetsuji, Murphy, Elizabeth, Steenbergen, Charles
Formato: Artigo
Idioma:Inglês
Publicado em: 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4006628/
https://ncbi.nlm.nih.gov/pubmed/24557881
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1161/CIRCRESAHA.114.303562
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