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TGFβ2 dictates disseminated tumour cell fate in target organs through TGFβ-RIII and p38α/β signalling
In patients non-proliferative disseminated tumour cells (DTCs) can persist in the bone marrow (BM) while other organs (i.e. lung) present growing metastasis. This suggested that the BM might be a metastasis “restrictive soil” by encoding dormancy-inducing cues in DTCs. Here we show in a HNSCC model...
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| Main Authors: | , , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2013
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4006312/ https://ncbi.nlm.nih.gov/pubmed/24161934 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ncb2861 |
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