Nrf2 Signaling Modulates Cigarette Smoke Induced Complement Activation in Retinal Pigmented Epithelial Cells

While cigarette smoking (CS) and dysregulated complement are thought to play a central role in age-related macular degeneration (AMD), their exact roles are unknown. The aim of this study is to determine if CS activates complement and if the antioxidant transcription factor Nrf2 modulates this respo...

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Bibliografiske detaljer
Main Authors: Wang, Lei, Kondo, Naoshi, Cano, Marisol, Ebrahimi, Katayoon, Yoshida, Takeshi, Barnett, Bradley P., Biswal, Shyam, Handa, James T.
Format: Artigo
Sprog:Inglês
Udgivet: 2014
Fag:
Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4006310/
https://ncbi.nlm.nih.gov/pubmed/24440594
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.freeradbiomed.2014.01.015
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