Chronic Cigarette Smoke Causes Oxidative Damage and Apoptosis to Retinal Pigmented Epithelial Cells in Mice

The purpose of this study was to determine whether mice exposed to chronic cigarette smoke develop features of early age-related macular degeneration (AMD). Two month old C57Bl6 mice were exposed to either filtered air or cigarette smoke in a smoking chamber for 5 h/day, 5 days/week for 6 months. Ey...

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Bibliographic Details
Main Authors: Fujihara, Masashi, Nagai, Norihiro, Sussan, Thomas E., Biswal, Shyam, Handa, James T.
Format: Artigo
Language:Inglês
Published: Public Library of Science 2008
Subjects:
Research Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC2518621/
https://ncbi.nlm.nih.gov/pubmed/18769672
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0003119
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