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Complex role of space in the crossing of fitness valleys by asexual populations

The evolution of complex traits requires the accumulation of multiple mutations, which can be disadvantageous, neutral or advantageous relative to the wild-type. We study two spatial (two-dimensional) models of fitness valley crossing (the constant-population Moran process and the non-constant-popul...

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Detalhes bibliográficos
Main Authors: Komarova, Natalia L., Shahriyari, Leili, Wodarz, Dominik
Formato: Artigo
Idioma:Inglês
Publicado em: The Royal Society 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4006240/
https://ncbi.nlm.nih.gov/pubmed/24671934
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1098/rsif.2014.0014
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