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Understanding MHC Class I Presentation of Viral Antigens by Human Dendritic Cells as a Basis for Rational Design of Therapeutic Vaccines

Effective viral clearance requires the induction of virus-specific CD8(+) cytotoxic T lymphocytes (CTL). Since dendritic cells (DC) have a central role in initiating and shaping virus-specific CTL responses, it is important to understand how DC initiate virus-specific CTL responses. Some viruses can...

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Detalhes bibliográficos
Main Authors: van Montfoort, Nadine, van der Aa, Evelyn, Woltman, Andrea M.
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4005948/
https://ncbi.nlm.nih.gov/pubmed/24795724
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fimmu.2014.00182
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