In Vivo Efficacy and Pharmacokinetics of AC98-6446, a Novel Cyclic Glycopeptide, in Experimental Infection Models
AC98-6446 is a novel semisynthetic derivative of a natural product related to the mannopeptimycins produced by Streptomyces hygroscopicus. Naturally occurring esterified mannopeptimycins exhibited excellent in vitro activity but only moderate in vivo efficacy against staphylococcal infection. The in...
محفوظ في:
| الحاوية / القاعدة: | Antimicrob Agents Chemother |
|---|---|
| المؤلفون الرئيسيون: | , , , |
| التنسيق: | Artigo |
| اللغة: | Inglês |
| منشور في: |
American Society for Microbiology (ASM)
2004
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| الموضوعات: | |
| الوصول للمادة أونلاين: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC400572/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/15105124/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/AAC.48.5.1708-1712.2004 |
| الوسوم: |
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