Mechanism of Action of the Mannopeptimycins, a Novel Class of Glycopeptide Antibiotics Active against Vancomycin-Resistant Gram-Positive Bacteria

The naturally occurring mannopeptimycins (formerly AC98-1 through AC98-5) are a novel class of glycopeptide antibiotics that are active against a wide variety of gram-positive bacteria. The structures of the mannopeptimycins suggested that they might act by targeting cell wall biosynthesis, similar...

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Main Authors: Ruzin, Alexey, Singh, Guy, Severin, Anatoly, Yang, Youjun, Dushin, Russell G., Sutherland, Alan G., Minnick, Albert, Greenstein, Michael, May, Michael K., Shlaes, David M., Bradford, Patricia A.
Formato: Artigo
Idioma:Inglês
Publicado: American Society for Microbiology 2004
Assuntos:
Mechanisms of Action: Physiological Effects
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC353120/
https://ncbi.nlm.nih.gov/pubmed/14982757
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.48.3.728-738.2004
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