Novel functional small RNAs are selectively loaded onto mammalian Ago1

Argonaute (Ago) proteins function in RNA silencing as components of the RNA-induced silencing complex (RISC). In lower organisms, the small interfering RNA and miRNA pathways diverge due in part to sorting mechanisms that direct distinct small RNA (sRNA) duplexes onto specific Ago-RISCs. However, su...

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Bibliografske podrobnosti
Main Authors: Yamakawa, Natsuko, Okuyama, Kazuki, Ogata, Jun, Kanai, Akinori, Helwak, Aleksandra, Takamatsu, Masako, Imadome, Ken-ichi, Takakura, Kohei, Chanda, Bidisha, Kurosaki, Natsumi, Yamamoto, Haruna, Ando, Kiyoshi, Matsui, Hirotaka, Inaba, Toshiya, Kotani, Ai
Format: Artigo
Jezik:Inglês
Izdano: Oxford University Press 2014
Teme:
RNA
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC4005649/
https://ncbi.nlm.nih.gov/pubmed/24627180
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gku137
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