The Trypanocide Diminazene Aceturate Is Accumulated Predominantly through the TbAT1 Purine Transporter: Additional Insights on Diamidine Resistance in African Trypanosomes

Resistance to diminazene aceturate (Berenil) is a severe problem in the control of African trypanosomiasis in domestic animals. It has been speculated that resistance may be the result of reduced diminazene uptake by the parasite. We describe here the mechanisms by which [(3)H]diminazene is transpor...

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Gorde:
Xehetasun bibliografikoak
Egile Nagusiak: de Koning, Harry P., Anderson, Laura F., Stewart, Mhairi, Burchmore, Richard J. S., Wallace, Lynsey J. M., Barrett, Michael P.
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: American Society for Microbiology 2004
Gaiak:
Mechanisms of Resistance
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC400564/
https://ncbi.nlm.nih.gov/pubmed/15105099
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.48.5.1515-1519.2004
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