Trypanocidal Activity of Melamine-Based Nitroheterocycles

A series of nitroheterocyclic compounds were designed with linkages to melamine or benzamidine groups that are known substrates of the P2 aminopurine and other transporters in African trypanosomes of the brucei group. Several compounds showed in vitro trypanotoxicity with 50% inhibitory concentratio...

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Detalhes bibliográficos
Publicado no:Antimicrob Agents Chemother
Main Authors: Stewart, Mhairi L., Bueno, Gorka Jimenez, Baliani, Alessandro, Klenke, Burkhard, Brun, Reto, Brock, Janice M., Gilbert, Ian H., Barrett, Michael P.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology (ASM) 2004
Assuntos:
Experimental Therapeutics
Acesso em linha:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC400563/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/15105128/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/AAC.48.5.1733-1738.2004
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