Mechanism of Action of the Ribopyranoside Benzimidazole GW275175X against Human Cytomegalovirus

New human cytomegalovirus (HCMV) therapies with novel mechanisms of action are needed to treat drug-resistant HCMV that arises during therapy with currently approved agents. 2-Bromo-5,6-dichloro-1-β-d-ribofuranosyl-1H-benzimidazole (BDCRB) is an effective anti-HCMV agent with a novel mechanism of ac...

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Bibliographic Details
Published in:Antimicrob Agents Chemother
Main Authors: Underwood, Mark R., Ferris, Robert G., Selleseth, Dean W., Davis, Michelle G., Drach, John C., Townsend, Leroy B., Biron, Karen K., Boyd, F. Leslie
Format: Artigo
Language:Inglês
Published: American Society for Microbiology (ASM) 2004
Subjects:
Antiviral Agents
Online Access:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC400548/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/15105116/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/AAC.48.5.1647-1651.2004
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