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Three-Parent IVF: Gene Replacement for the Prevention of Inherited Mitochondrial Diseases
Mitochondrial dysfunction has been recognized as a significant cause of a number of serious multi-organ diseases. Tissues with a high metabolic demand such as brain, heart, muscle, CNS are often affected. Mitochondrial disease can be due to mutations in mitochondrial DNA (mtDNA) or in nuclear genes...
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| Main Authors: | , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado: |
2014
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| Assuntos: | |
| Acceso en liña: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4005382/ https://ncbi.nlm.nih.gov/pubmed/24382342 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.fertnstert.2013.11.030 |
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