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Clinical Consequences of Mutations in Thyroid Hormone Receptor-α1
Thyroid hormone (TH) exerts its biological activity via the TH receptors TRα1 and TRβ1/2, which are encoded by the THRA and THRB genes. The first patients with mutations in THRB were identified decades ago. These patients had a clinical syndrome of resistance to TH associated with high serum TH and...
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| Main Authors: | , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
S. Karger AG
2014
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4005264/ https://ncbi.nlm.nih.gov/pubmed/24847461 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1159/000360637 |
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