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Preclinical evaluation of marketed sodium channel blockers in a rat model of myotonia discloses promising antimyotonic drugs

Although the sodium channel blocker mexiletine is considered the first-line drug in myotonia, some patients experiment adverse effects, while others do not gain any benefit. Other antimyotonic drugs are thus needed to offer mexiletine alternatives. In the present study, we used a previously-validate...

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Main Authors: Desaphy, Jean-François, Carbonara, Roberta, Costanza, Teresa, Conte Camerino, Diana
Format: Artigo
Jezik:Inglês
Izdano: Academic Press 2014
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC4004800/
https://ncbi.nlm.nih.gov/pubmed/24613829
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.expneurol.2014.02.023
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