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Preclinical evaluation of marketed sodium channel blockers in a rat model of myotonia discloses promising antimyotonic drugs

Although the sodium channel blocker mexiletine is considered the first-line drug in myotonia, some patients experiment adverse effects, while others do not gain any benefit. Other antimyotonic drugs are thus needed to offer mexiletine alternatives. In the present study, we used a previously-validate...

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Detalhes bibliográficos
Main Authors: Desaphy, Jean-François, Carbonara, Roberta, Costanza, Teresa, Conte Camerino, Diana
Formato: Artigo
Idioma:Inglês
Publicado em: Academic Press 2014
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4004800/
https://ncbi.nlm.nih.gov/pubmed/24613829
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.expneurol.2014.02.023
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